Buch

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Übersicht

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Verlag	:	Springer Netherland
Buchreihe	:	Developments in Cardiovascular Medicine (Bd. 2)
Sprache	:	Englisch
Erschienen	:	06. 11. 2011
Seiten	:	555
Einband	:	Kartoniert
Höhe	:	244 mm
Breite	:	156 mm
Gewicht	:	917 g
ISBN	:	9789400987982
Sprache	:	Englisch

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Inhaltsverzeichnis

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Section 1: Cardiac Muscle Mechanics: From the Fiber Down to the Sarcomere.- 1.1 The coming of age of cardiac muscle mechanics.- 1.2 The importance of passive elements in the contraction of the heart.- 1.3 Tension development and sarcomere length in rat cardiac trabe-culae: evidence of length-dependent activation.- 1.4 Inseparability between preload and contractility effects on pressure development in the isovolumically contracting isolated rabbit heart.- 1.5 Force-velocity-length relations in cardiac muscle segments.- 1.6 Theoretical and experimental force-velocity relations of the ventricular myocardium.- 1.7 Time course of changes in action potential duration and ejection shortening during regional transient ischaemia of pig ventricle in situ.- 1.8 A quantitative analysis of the force transients of skeletal muscle in response to quick changes in length.- Section 2: Cardiac Chamber Dynamics: From the Fiber up to the Myocardium.- 2.1 A fundamental similarity between isolated muscle mechanics and cardiac chamber dynamics.- 2.2 The chamber dynamics of the intact left ventricle.- 2.3 LV wall fibre pathways for impulse propagation.- 2.4 Transmural course of stress and sarcomere length in the left ventricle under normal hemodynamic circumstances.- 2.5 The role of wall thickness in the relation between sarcomere dynamics and ventricular dynamics.- 2.6 A model for left ventricular contractions based on the sliding filament theory.- Section 3: Pump Function and Filling: Interaction with the Low Pressure System.- 3.1 Dynamic determinants of left ventricular filling: an overview.- 3.2 Effects of the pericardium on left ventricular performance.- 3.3 Blood flow dynamics during the human left ventricular filling phase.- 3.4 Relaxation of the left ventricle.- 3.5 Intramural stress and strain analysis in the intact heart.- 3.6 Effects of intravenous isosorbide dinitrate on filling pressures and pump function in patients with refractory pump failure.- 3.7 Transfer function model of the heart.- 3.8 Dynamics of sequential large pulmonary emboli.- Section 4: Pump Function and Ejection: Interaction with Systemic Load and Coronary Perfusion.- 4.1 Pump function and its interaction with the systemic load.- 4.2 Quantification of extravascular coronary resistance.- 4.3 Studies on the optimal matching between heart and arterial system.- 4.4 End-systolic pressure as direct determinant of stroke volume from fixed end-diastolic volume in isolated canine left ventricle.- 4.5 Pump function of the left ventricle evaluated from pressure-volume loops.- 4.6 Simulation study of flow distribution across myocardium.- 4.7 Experimental studies: the appearance of large coronary arteries during arteriography.- 4.8 Hemodynamic effects of reductions in coronary blood flow caused by mechanical stenosis and platelet aggregates forming in dog coronary arteries.- Section 5: Measuring Cardiac Performance: Aims and Validity of Invasive and Noninvasive Measurement.- 5.1 Isaac Starr Lecture: Invasive and noninvasive monitoring of cardiovascular dynamics in clinical practice.- 5.2 Measuring cardiac performance: aims and validity of invasive and noninvasive assessment.- 5.3 The clinical usefulness of noninvasive and invasive tools in the assessment of left ventricular function in myocardial infarction.- 5.4 Model-based hemodynamic indicators of left ventricular performance.- 5.5 Comparative evaluation of myocardial performance factors.- 5.6 Circulatory changes during isometric exercise measured by transcutaneous aortovelography.- 5.7 Validity of parameters of ventricular performance determined by radiocardiography in patients with coronary artery disease.- 5.8 Assessment of the dynamics of cardiac responses to positive inotropic agents.- 5.9 Assessment of cardiac function in the dog by cross-sectional echocardiography.- 5.10 Dynamics of the left ventricular centre of mass in intact unanaesthetized man in the presence and absence of wall motion abnormalities.- 5.11 Cardiac pump function by ballistocardiogram: normal standards and comparison with coronary arteriograms.- Section 6: Energy Losses: Hemodynamics of Valves.- 6.1 Konrad Witzig Memorial Lecture: Some fluid mechanic theories and their application to the design of heart valves and membrane lungs.- 6.2 Fluid dynamics in the aorta.- 6.3 The closing behaviour of the natural aortic valve.- 6.4 Fluid mechanics of the aortic valve.- 6.5 Mechanical energy losses resulting from stenosis of semilunar valves.- 6.6 Pressure-flow relations and energy losses across prosthetic mitral valves: in vivo and in vitro studies.- 6.7 Blood flow velocity in subclavian artery and through mitral valve measured with transcutaneous Doppler ultrasound. The effects of exercise and mitral valve disease.- Closing Lecture: Approaching the heart of the matter.

Deine Buchhandlung

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